Clive Davis; Why Things Catch On; the Novel Frances and Bernard; Leaving the Westboro Baptist Church

Legendary music producer Clive Davis talks about working with some of music?s biggest names over the last five decades, including Aretha Franklin, Janis Joplin, and Kelly Clarkson. ?Marketing professor Jonah Berger helps us understand why some products and ideas catch on while others don?t.?Carlene Bauer talks about her latest novel,?Frances and Bernard.?Plus, one woman?s experience growing up in the Westboro Baptist Church, known for its high-profile protests and extreme beliefs.

Source: http://www.wnyc.org/shows/lopate/2013/may/27/

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Radioactive nanoparticles target cancer cells

May 21, 2013 ? Cancers of all types become most deadly when they metastasize and spread tumors throughout the body. Once cancer has reached this stage, it becomes very difficult for doctors to locate and treat the numerous tumors that can develop. Now, researchers at the University of Missouri have found a way to create radioactive nanoparticles that target lymphoma tumor cells wherever they may be in the body.

Michael Lewis, an associate professor of oncology in the MU College of Veterinary Medicine, says being able to target secondary tumors is vital to successfully treating patients with progressive cancers.

"Depending on the type of cancer, primary tumors usually are not the cause of death for cancer patients," Lewis said. "If a cancer metastasizes, or spreads creating hard-to-find tumors, it often becomes fatal. Having a way to identify and shrink these secondary tumors is of utmost importance when fighting to save people with these diseases."

In an effort to find a way to locate and kill secondary tumors, Lewis, in collaboration with J. David Robertson, director of research at the MU Research Reactor and professor of chemistry in the College of Arts and Science, have successfully created nanoparticles made of a radioactive form of the element lutetium. The MU scientists then covered the lutetium nanoparticles with gold shells and attached targeting agents.

In previous research, Lewis has already proven the effectiveness of similar targeting agents in mice and dogs suffering from tumors. In that research, the targeting agents were attached to single radioactive atoms that were introduced into the bodies of animals with cancer. The targeting agents were able to seek out the tumors existing within the animals, which were then revealed through radio-imaging of those animals.

In their current research, the MU scientists have shown the targeting agents can deliver the new radioactive lutetium nanoparticles to lymphoma tumor cells without attaching to and damaging healthy cells in the process. Robertson says this is an important step toward developing therapies for lymphoma and other advanced-stage cancers.

"The ability to deliver multiple radioactive atoms to individual cancer cells should greatly increase our ability to selectively kill these cells," Robertson said. "We are very optimistic about the synergy of combining the targeting strategy developed in Dr. Lewis's lab with our work on new radioactive nanoparticles."

Lewis has been invited to present his research at the City of Hope National Medical Center this June in Duarte, Calif.

This study is an example of the collaborative research taking place in the One Health, One Medicine area of Mizzou Advantage. The early-stage results of this research are promising. If additional studies, including animal studies, are successful within the next few years, the researchers will request permission from the federal government to begin human drug development. After this status has been granted, Lewis and Robertson may conduct human clinical trials with the hope of developing new treatments.

Lewis also is a principal investigator in the Research Service at the Harry S. Truman Memorial Veterans' Hospital. This research was supported by awards from the National Cancer Institute and the Department of Veterans Affairs as well as resources made available by Department of Veterans Affairs through use of facilities at the Harry S. Truman Memorial Veterans' Hospital in Columbia, Mo.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/iaT3hmvMAtI/130521132229.htm

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Big bucks to be made on small screen | Stuff.co.nz

Wellington's screen industry is hoping the Government will increase incentives for international television production to encourage long-form overseas shows to film here.

Raunchy swords and sorcery drama Game of Thrones films many scenes in Northern Ireland, where it received ?9.25 million of government grants. Filming of its first three seasons generated ?65m for the local economy. (Game of Thrones has run on Sky TV in New Zealand.)

Under the Screen Production Incentive Fund, television series filmed here with significant New Zealand content currently qualify for a grant of 20 per cent of the total local production cost, only half the 40 per cent rebate feature films are eligible for.

With the Large Budget Screen Production Grant, feature films and television series without significant New Zealand content need to have production expenditure of at least $15m to qualify for a 15 per cent grant.

The Government is considering reviewing the incentives, seeking advice from Film New Zealand. It has "an interest in encouraging more international television production", according to Film NZ chief executive Gisella Carr.

She said Game of Thrones' economic impact on Ireland showed what television production could do for a region and countries around the world were targeting international television production work.

"Television builds infrastructure, as has been evident in New Zealand's own international television history. Rob Tapert's television production in Auckland starting with Xena and Hercules has been vital to growing the industry.

"Spartacus injected more than $200m into the Auckland economy. Jane Campion's Top of the Lake [filmed in the South Island] . . . shone the spotlight firmly on New Zealand."

Screen Production and Development Association chief executive Penelope Borland said current incentives were only "marginal".

She believed long-form television being made in New Zealand for international markets was hugely important for ongoing work and the sustainability and growth of the local industry.

"You only need to look at the employment and economic impact of four seasons of Spartacus in Auckland - 350 permanent crew, 400 casual crew, 1000 New Zealand and Auckland specific suppliers," she said.

" The sooner incentives are improved to attract more longform TV the better. There is huge competition internationally.

"The relatively high New Zealand dollar for the United States and elsewhere and lack of standing stage infrastructure in Auckland to meet the needs of any production of scale are also barriers.

"In Wellington, Avalon Studios could be adapted for long-form TV production."

Investor John Feast, who led the group that bought Avalon Studios in Lower Hutt last year, said long-form television and feature films should receive equal grants and concessions to provide a location for United States, Asian, European and Australian television production.

WELLINGTON TV

Pukeko Pictures' The WotWots signed up another series with UK Channel 5 Milkshake Lotto is filmed at Avalon Studios Country Calendar and Praise Be are produced at Avalon Studios Thunderbirds Are Go being made by Britain's ITV in a co-production involving Pukeko Pictures and Weta.

- ? Fairfax NZ News

Source: http://www.stuff.co.nz/business/industries/8695895/Big-bucks-to-be-made-on-small-screen

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PAC Plus polls Latinos in Texas (Offthekuff)

Share With Friends: | | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/307228738?client_source=feed&format=rss

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New Flickr Walkthrough: So Pretty, So Much, So Free

After languishing for years as a neglected acquisition, Flickr has finally been given the jumpstart it so desperately needed and deserved. As of right now, not only to you get a free terabyte of storage and extremely high res photo uploads, you get it in pretty stellar package. Here's what you're dealing with.

While the new Flickr is definitely a feast for the eyes, it seems to be very incomplete so far, as much of the core functionality is still stuck in the previous interface style. It seems safe to assume that eventually the whole experience will be pulled together in the spirit of the new, and based on how sumptuous those parts look already, we can't wait for that to happen.

Source: http://gizmodo.com/new-flickr-walkthrough-so-pretty-so-much-so-free-508964659

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Oklahoma tornadoes: how you can help

The American Red Cross, Salvation Army, and United Way are among organizations accepting donations to help those affected by tornadoes in Moore, Okla., and nearby areas.

By Allison Terry,?Correspondent / May 21, 2013

An American flag blows in the wind at sunrise atop the rubble of a destroyed home a day after a tornado moved through Moore, Okla., Tuesday. The monstrous tornado roared through the Oklahoma City suburb Monday, flattening entire neighborhoods and destroying an elementary school.

Brennan Linsley/AP

Enlarge

A number of relief organizations are responding to the disaster in Moore, Okla., where a devastating tornado destroyed hundreds of homes Monday, hit at least two elementary schools hard, and killed at least 24 people. The general public can help with recovery efforts through these organizations, which already are helping families and supporting the first responders.

Skip to next paragraph Allison Terry

Correspondent

Allison Terry works on national news desk for the Christian Science Monitor. She also contributes to the culture section and Global News blog.

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The American Red Cross has opened shelters in Moore, a suburb of Oklahoma City, and it has deployed emergency response vehicles to provide hot meals for displaced people and emergency workers. To support the relief efforts, the Red Cross is accepting online donations. People can send the text message ?REDCROSS? to 90999 to immediately donate $10, or they can call 800-REDCROSS.

The Salvation Army has also sent disaster response teams to Moore, including mobile feeding units. It is working in several counties in Oklahoma affected by tornadoes both Sunday and Monday. It is accepting online donations, and it also has a text-message donation option: text ?STORM? to 80888. Donate via phone by calling 800-SALARMY.

The United Way of Central Oklahoma has set up a fund for people to directly support the tornado recovery efforts of its partner agencies working in Moore and Shawnee, Okla. The organization prefers online donations.?

Save the Children says it's sending?help?to affected families in Moore, providing kits for shelters to create safe play zones for children, as well as hygiene materials for infants and toddlers. Save the Children CEO Carolyn Miles says experience shows that children are most vulnerable during emergencies. Donate online?or call 800-728-3843.

Operation USA is a Los Angeles-based relief agency that provides emergency aid to community-based health organizations. It is also collecting corporate donations of bulk quantities of disaster-appropriate supplies to distribute in Oklahoma. Donate online, send the text message ?AID? to 50555, or call 800-678-7255.

The Southern Baptist Convention has deployed more than 80 volunteers to support disaster relief efforts. It provides various services including cleanup, tree removal, laundry services, and food for victims. The Oklahoma Baptist Disaster Relief ministry accepts online donations, or people can call (405) 942-3800.

Beyond the official relief organizations and first responders, Oklahoma officials are asking people to keep the damaged areas clear.

?I want to encourage all Oklahomans that can to stay away. We have lots of law enforcement, emergency personnel that are working on the sites,? Gov. Mary Fallin (R) said Monday.

Governor Fallin deployed the Oklahoma National Guard to the disaster areas and has called for out-of-state search-and-rescue teams to assist in the recovery efforts. Texas Gov. Rick Perry (R) sent an elite search-and-rescue team including hazardous material specialists, structural engineers, and 70 first responders who are trained in victim extraction and medical treatment. The same team responded to the fertilizer plant explosion in West, Texas, last month.

President Obama declared Oklahoma a major disaster area and ordered federal aid be sent to help local and state responders. ?As a nation, our full focus right now is on the urgent work of rescue, and the hard work of recovery and rebuilding that lies ahead,? he said at a press conference Tuesday morning.

Federal Emergency Management Agency director Craig Fugate is to arrive in the state Tuesday to oversee the distribution of federal aid.

Moore Mayor Glenn Lewis, who was also mayor during a similar devastating tornado in 1999, said the city was quickly beginning work on the recovery.

"We've already started printing the street signs," he said. "It took 61 days to clean up after the 1999 tornado. We had a lot of help then. We've got a lot of help now.?

??Material from the Associated Press contributed to this report.?

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/s32ceU4SYFo/Oklahoma-tornadoes-how-you-can-help

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Burstly Debuts Its Testing-To-Revenue Restructure, Opens SkyRocket Monetization To All

Burstly's grand vision coming out of its TestFlight acquisition is getting full reveal today with the announcement of the company's new corporate structure, which rebrands Burstly's monetization tools as SkyRocket, and opens them up to all mobile developers and publishers with a new self-serve option, whereas previously they'd been accessible only to the biggest fish in the app ecosystem pond.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/7U5DPzdV3as/

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